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Haematology Department information

The Department provides a comprehensive clinical, analytical and interpretative service in all aspects of Haematology to UHBristol, surrounding GPs and act as a referral centre for other hospitals locally, regionally and through out the UK.

Senior Staff

Head of Department - Dr Andrew Stewart
Laboratory Manager - Mrs Elizabeth Worsam
Consultant Haematologists - Dr Priyanka Mehta, Dr Andrew Mumford, Dr Tom Latham

Analytical Service 

The department provides a comprehensive repertoire of tests delivered by six sections in the laboratory.

 1. Haematology (Section Leader Mr Mark Nicholas)

The Haematology section offers routine Full blood counts, Blood film and CSF cytospin (from leukaemia, lymphoma patients) examinations, Bone marrow film staining,  Malaria screening and species identification, ESRs, Plasma viscosities, Haemoglobinpathy Screening including Antenatal Screening,and G6PDH quantitation.

 

 2. Blood Transfusion (Blood Bank Manager Mrs Adele Wardle)

The Blood Transfusion offers routine automated and manual blood grouping and antibody screening and identification. Red cell electronic issue. Red cell and granulocyte cross matching is available. Products such as FFP, cryoprecipitate, platelet concentrates, prophylactic anti-D, HAS and clotting factor concentrates are also available.

 

 3. Coagulation (Section Leader Mr Chris Reilly-Stitt)

The Coagulation section offers both routine and specialised coagulation investigations including INRs, APTTs for anticoagulant control and monitoring, fibrinogens, D Dimers to assist in the investigation of VTE, and factor assays. Thrombophilia investigations and platelet aggregation studies are also performed.

 

 4. Immunology (Section Leader Mr Chris Reilly-Stitt)

The Immunology section offers the following specialist tests; Autoimmune profile (antinuclear antibodies, mitochondrial antibodies, parietal cell antibodies, smooth muscle antibodies and Liver, Kidney Microsomal antibodies), Anti-neutrophil cytoplasmic antibodies (ANCA), Anti-dsDNA antibodies, Anti Cardiolipin antibodies, Exctractable nuclear (ENA)antibodies, Centromere antibodies Intrinsic factor antibodies, Glandular fever testing and Rheumatoid factor

 

   5. Molecular Haematology (Section Leader Mr Tim Clench)

The Molecular Haematology section offers a comprehensive specialist molecular diagnostic service to aid in the diagnosis of haematological malignancy.  Tests offered are: Prothrombin gene mutation analysis, Factor V Leiden mutation analysis, Haemochromatosis mutation analysis. Thiopurine methyltransferase (TPMT) genotyping, Jak2/Mpl mutation analysis, FLT3 gene analysis, Nucleophosmin (NPM1) mutation analysis, Leukaemia associated chromosomal abnormalities, Quantitative PCR for bcr-abl, Clonal rearrangement of the T-cell receptor and analysis of IgVH mutational status in CLL.

 

  6. Flow Cytometry Section (Section Leader Dr Ulrika Johansson)

 The Flow Cytometry section offers the following tests; Leukaemia and lymphoma immunophenotyping including Minimal Residual Disease assays for Acute Leukaemia and CLL, CSF analysis, CD34 stem cell enumeration, foetal maternal haemorrhage quantitation and Paroxysmal Nocturnal Haemoglobinuria (PNH). 

Out of Hours Sevice

The Haematology department provides a full 24 hour service for routine tests. For specialised tests, discussion with the out of hours Biomedical Scientist (X 22579) and the on-call Haematologist (contactable via the switchboard) are required.

 

Clinical Services

  

The department provides specialist advice on the appropriateness and interpretation of Haematology tests via Biomedical Scientists and Clinical Haematology Staff.

 

Research and Development
The department encourages R&D and regularly presents its work at national and international meetings. The department's USTAR (Unit for Studies, Trials and Research) service also facilitates the undertaking of clinical trails and research projects through out the trust.

Training and Development
The department is fully accredited for the training of all laboratory staff. It has extensive inputs into both under- and post-graduate teaching at the Universities of Bristol, West of England and Bath.

 

For more information on our services choose from the following links: