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Aims of the service: 

  • Provide an efficient comprehensive diagnostic service for haematological malignancies
  • Provide effective communication with clinical haematologists and multidisciplinary meetings (MDTs) to support an accurate diagnosis and aid patients in their management pathway
  • Provide teaching and training of medical and laboratory staff
  • Provide support for accurate data for the Somerset Cancer Registry
  • Provide and implement state of the art tecnologies as appropriate
    Foster  research links with Universities


All bone marrow samples undergo a systematic initial evaluation  involving clinical, morphological and flow assessments. Samples for molecular and cytogenetic analysis are stored at this stage.

Results from the initial screen allow a decision algorithm to be followed and samples are processed if required for molecular diagnostics and if necessary sent for cytogenetics at either Southmead Hospital, Bristol or Salisbury depending on the investigations required.

Results are reviewed and integrated in a weekly diagnostic MDT meeting attended by three consultant haematologists with expertise in molecular and flow cytometry, histopathology  and haematology training grade. This allows tracking of samples in the diagnostic pathway and culminates in a final electronic report integrating all of the diagnostic information. 

These results are fed into two weekly clinical MDTs for patients with Lymphoma and Myeloma/Leukaemia where the clinical management plan for the patient is decided.